Module 1 Assignment 605.451 – Principles of Computational Biology Solved

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1. What is the central dogma of molecular biology? (50 points)
2. In theory, how many codons can you have given that there are only 4 different types of nucleotides
(ATGC) and each codon contains 3 nucleotides? (25 points)
3. We know that the human genome contains about 3 billion nucleotides. Suppose all 3 billion
nucleotides are on one single strand of DNA; how many different sequences can you have, in
theory? (25 points)